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Research progress of signal pathways related to the pathogenesis of uric acid nephropathy
Author(s): 
Pages: 113-116
Year: Issue:  2
Journal: Qilu Pharmaceutical Affairs

Keyword:  尿酸性肾病发病机制信号通路;
Abstract: 尿酸性肾病是由于血尿酸产生过多或排泄减少形成高尿酸血症所致的肾损害,通常称为痛风肾病.尿酸性肾病可由尿酸水平过高介导激活的多种信号通路和炎症因子诱导发病.本综述分别以"尿酸""肾病"或"尿酸性肾病""uric acid nephropathy"等为关键词在中国知网、PubMed等数据库中查询近十年关于尿酸性肾病发病机制相关信号通路的文献,并选取具有代表性的进行整合综述.本文通过研究尿酸性肾病发病机制和相关信号通路的进展,整合了尿酸性肾病发病的具体机制,并且以多种信号通路作用为思路提供治疗尿酸性肾病的新型治疗手段.
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