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Anti-complementary activities of constituents from Waldheimia glabra
Author(s): 
Pages: 1-5,15
Year: Issue:  1
Journal: Qilu Pharmaceutical Affairs

Keyword:  西藏扁芒菊抗补体活性酚酸黄酮;
Abstract: 目的 研究西藏扁芒菊[Waldheimia glabra(Decne.)Rgl.]全草的化学成分及其抗补体活性.方法 通过溶血实验,对西藏扁芒菊醇提物进行抗补体活性测试,并以抗补体活性作为分离导向进行分离与纯化,以现代谱学技术鉴定结构,确定抗补体活性成分.结果 从西藏扁芒菊95%乙醇提取物中分离得到10个抗补体活性物质,包括5个酚酸、3个黄酮、1个倍半萜和1个酪醇.结论 酚酸与黄酮是主要的抗补体活性成分,构效关系分析显示咖啡酰基对于抗补体活性有重要的作用.
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