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Gut microbes—new target for atherosclerosis
Author(s): 
Pages: 411-415
Year: Issue:  7
Journal: Qilu Pharmaceutical Affairs

Keyword:  肠道微生物动脉粥样硬化短链脂肪酸三甲胺-N-氧化物;
Abstract: 肠道作为机体最大的微生物群系统,肠道内微生物组成和丰度发生改变与机体的健康密切相关.动脉粥样硬化的危险因素(高龄、肥胖、饮食习惯等)诱导肠道生态失衡;肠道微生物代谢产物(短链脂肪酸、三甲胺-N-氧化物等)的改变,诱导动脉粥样硬化的发生和发展.本文就肠道微生物及其代谢产物在动脉粥样硬化中的作用和以肠道为靶点的治疗、干预的研究进展做一综述.
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