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Drugs of promoting liver regeneration and their mechanisms
Author(s): 
Pages: 486-489
Year: Issue:  8
Journal: Qilu Pharmaceutical Affairs

Keyword:  再生修复促肝再生药物机制;
Abstract: 肝脏是哺乳动物中具有高度再生能力的器官.当肝脏受损时,静息的肝细胞接受刺激而重新进入细胞周期,使肝脏再生并部分恢复肝功能.然而,肝再生反应并不总是成功的,有时肝损伤会发展为进行性损伤并诱发严重的肝衰竭.对于部分肝脏切除手术后的肝硬化或癌症患者而言,寻找既能保护肝功能,又能提高肝脏再生能力的药物和方法具有重要的临床意义.本文就文献报道的促肝再生作用的药物及其作用机制做一综述,旨在为开发有效的药物治疗提供新见解.
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