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Literature analysis of 59 cases of drug-induced pancreatitis
Author(s): 
Pages: 175-178
Year: Issue:  3
Journal: Qilu Pharmaceutical Affairs

Keyword:  药源性胰腺炎文献分析药品不良反应;
Abstract: 目的 探讨药源性胰腺炎发生的特点,为临床安全用药提供参考.方法 检索中国期刊全文数据库1981~2018年报道的药源性胰腺炎个案病例文献,并对其进行汇总分析.结果 共纳入56篇文献,59例病例.发生药源性胰腺炎较多的药物为抗肿瘤药物(28.81%)、抗感染药物(23.73%)及激素相关性药物(15.25%);10岁以下患者构成比最高(22.03%).59例患者中,31例发生在给药1周以内(52.54%),54例患者治愈(91.53%),4例患者死亡(6.78%),情况不明患者1例(1.69%).结论 左旋门冬酰胺酶、替加环素、利福平及泼尼松等易诱发药源性胰腺炎,临床应用以上药物时需密切关注患者症状.
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