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Effect of Compound Trivitamin and Calcium Pantothenate Syrup on functional dyspepsia rats with spleen deficiency
Author(s): 
Pages: 80-83,90
Year: Issue:  2
Journal: Qilu Pharmaceutical Affairs

Keyword:  复方三维右旋泛酸钙糖浆功能性消化不良淀粉酶胃泌素血管活性肽;
Abstract: 目的 研究复方三维右旋泛酸钙糖浆对脾虚型功能性消化不良(FD)大鼠的影响.方法 将48只SD大鼠随机分为6组:正常组、模型组、健胃消食片组(0.65 g·kg-1)、复方三维右旋泛酸钙糖浆高、中、低剂量组(2.70、5.40、10.80 g·kg-1),除正常组外,其余各组采用大黄+竭力游泳+控制饮食法复制脾虚功能性消化不良大鼠模型.各组分别灌胃给药14 d后,测定大鼠体重、脾脏指数、胸腺指数、小肠推进率,并检测尿D-木糖及血清淀粉酶、胃泌素、血管活性肽水平.结果 复方三维右旋泛酸钙糖浆能显著增加脾虚型功能性消化不良大鼠体重、脾脏指数、胸腺指数及小肠推进率,提高尿D-木糖量及血清淀粉酶和胃泌素水平,同时降低血清血管活性肽含量.结论 复方三维右旋泛酸钙糖浆可通过调节胃肠运动及小肠吸收功能起到改善功能性消化不良的作用.
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