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Advances in anti-tumor effects of ursolic acid and its derivatives
Author(s): XIANG Runqing, FAN Yuan
Pages: 63-
69
Year: 2019
Issue:
2
Journal: Qilu Pharmaceutical Affairs
Keyword: 熊果酸; 衍生物; 抗肿瘤;
Abstract: 熊果酸(ursolic acid,UA)是一种五环三萜类化合物,广泛存在于夏枯草、女贞子等多种药用植物中,具有多种生物活性.体内外研究表明,熊果酸抗瘤谱广,且对正常细胞毒性低,是一种理想的天然抗肿瘤候选药物,进行结构改造后具有更广泛的抗肿瘤活性.现综合国内外文献报道,对熊果酸及其衍生物抗肿瘤的作用进行综述.
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