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Amino acid industry status and strain breeding technology
Pages: 110-114
Year: Issue:  2

Keyword:  amino acidtraditional strain breedingmetabolic engineering strain breedinggenome editingprecise metabolic regulation;
Abstract: This paper summarized the amino acid production capacity , production and export volumn of China in 2017 . The breeding technologies of amino acid producing strains were elucidated . The traditional strain breeding technology has not been out-of-date . Instead , it should be integrated into the study of reverse metabolic engineering .Metabolic engineering has achieved great progress through many years'development ,and moved into systematic metabolic engineering .Meanwhile ,the evolutionary metabolic engineering has shown great potential .The construction of industrial strains is often operated at the genome level .Therefore ,this paper introduces the genome editing technologies of Escherichia coli and Corynebacterium glutamicum . Finally ,precise metabolic regulation technologies are briefly introduced ,and a case study is also provided .
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