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Study on preparation process of Sechang Capsules
Pages: 520-522
Year: Issue:  9
Journal: Qilu Pharmaceutical Affairs

Keyword:  涩肠胶囊制备工艺低温间歇灭菌法;
Abstract: 目的 对涩肠胶囊的制备工艺进行研究.方法 通过粉碎及灭菌试验、水煎煮提取试验、水煎液的浓缩试验、颗粒制备工艺的试验、胶囊填装试验,制备涩肠胶囊.结果 本试验木香的平均出粉率为97.7%;采用低温间歇灭菌法,加热和培育连续操作3次;加水量选择"10+8"倍量;以4%聚乙烯吡咯烷酮(PVP)无水乙醇溶液为黏合剂,(45±5)℃下干燥时间定为1.5 h.结论 该工艺合理可行,适用于涩肠胶囊的生产.
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