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Research progress on pharmacokinetic of andrographolide and its derivatives
Author(s): 
Pages: 669-672,678
Year: Issue:  11
Journal: Qilu Pharmaceutical Affairs

Keyword:  穿心莲内酯衍生物代谢产物药代动力学;
Abstract: 穿心莲内酯为从爵床科植物穿心莲中提取得到的二萜内酯类化合物,是中药穿心莲的主要有效成分之一.近年研究表明,其多种衍生物在溶解性等方面优于原型药物,促使含穿心莲内酯及其衍生物的药物在临床上被广泛应用.该文阐述了穿心莲内酯及其衍生物的药代动力学研究进展,以为这一天然活性成分的开发和利用提供依据.
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