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Study on the extraction technology and anti-inflammatory activity of the effective components in Echinacea purpurea flower
Author(s): 
Pages: 139-141,145
Year: Issue:  3
Journal: Qilu Pharmaceutical Affairs

Keyword:  紫锥菊菊苣酸正交试验抗炎活性;
Abstract: 目的 研究临沂引种紫锥菊花中药效成分的最佳提取工艺及其抗炎活性.方法 采用L9正交试验法筛选,通过高效液相色谱仪,用提取物中菊苣酸含量为量化指标进行量化,确定最佳提取工艺.耳肿胀和足跖肿胀试验确定紫锥菊花的抗炎活性.结果 紫锥菊花中药效成分的最佳提取工艺为70℃时用20倍量60%乙醇提取120 min提取2次,菊苣酸得率为2.34%.紫锥菊花的乙醇提取物在试验剂量表现出较好抗炎活性.结论 该方法提取紫锥菊的药效成分的工艺简便,污染少,可用于工业化生产.紫锥菊花的乙醇提取物具有较好的抗炎活性.
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