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The immunoloregulation of mushroom polysaccharides and tremella polysaccharides for mouse loading tumor
Author(s): 
Pages: 730-731
Year: Issue:  10
Journal: ZHEJIANG CLINICAL MEDICAL JOURNAL

Keyword:  复合多糖食药用菌免疫功能肿瘤;
Abstract: 目的探讨复合多糖对S180荷瘤小鼠免疫功能的影响.方法(1)模型:S180荷瘤小鼠动物模型;(2)免疫检测方法:溶血素测定,T淋巴细胞转化功能测定,腹腔巨噬细胞吞噬功能测定.(3)受试药物及给药方法:复合多糖口服.结果复合多糖以0.75g/kg剂量灌胃荷瘤小鼠,可明显提高血清溶血素(p<0.05)和T淋巴细胞转化功能(p<0.05),表明该制剂可明显提高荷瘤小鼠的体液和细胞免疫功能.同时以1.5g/kg和0.75g/kg剂量可明显提高荷瘤小鼠的腹腔吞噬细胞功能(p<0.05~0.01),表明该制剂对非特异性免疫有明显的促进作用.结论复合多糖对肿瘤机体免疫功能有明显的促进作用.
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