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The clinical analyses of nitroglycerin for pregnant hypertension
Author(s): 
Pages: 747-748
Year: Issue:  10
Journal: ZHEJIANG CLINICAL MEDICAL JOURNAL

Keyword:  妊高征硝酸甘油硫酸镁血小板凝集率尿蛋白;
Abstract: 目的研究硝酸甘油在治疗妊高征中的作用.方法选择中、重度妊高征患者113例;其中硫酸镁组56例,硝酸甘油组57例.对以上两组检测血小板凝集率,检测脐动脉收缩期与舒展期(S/D)比值和阻力指数,记录血压变化,测定24h尿蛋白.结果⑴硝酸甘油组用药后血小板凝集率明显降低,用药前后比较,差异有极显著性(P<0.01);硫酸镁组则无明显改变.⑵硝酸甘油组及硫酸镁组用药后S/D比值及阻力指数均降低,用药前后比较,差异均有显著性(P<0.05).⑶硝酸甘油组用药后血压降低,用药前后比较,差异有显著性(P<0.05);而硫酸镁组用药后血压变化不明显.⑷硫酸镁组与硝酸甘油组用药后24h尿蛋白定量均降低,用药前后比较,差异均有极显著性(P<0.01).结论硝酸甘油有抑制血小板凝聚、降低胎儿-胎盘循环阻力、降低血压及减少尿蛋白的作用,能改善妊高征患者的病理状态,有治疗作用.
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