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Optimization of extraction process for astragaloside in Feiwei Granules by supercritical CO2extraction technique
Author(s): 
Pages: 718-720
Year: Issue:  12
Journal: Qilu Pharmaceutical Affairs

Keyword:  肺痿颗粒黄芪甲苷超临界萃取法正交试验;
Abstract: 目的 优化肺痿颗粒中黄芪甲苷的超临界CO2萃取最佳工艺.方法 以黄芪甲苷的含量为指标,选取粉碎粒度、萃取时间、夹带剂浓度和夹带剂流速为影响因素,采用L9(34)正交试验法,优化提取工艺.结果 处方最佳提取工艺为粉碎粒度40目、提取时间1.5 h、夹带剂浓度95%乙醇和夹带剂流速10 mL·min-1进行超临界萃取.结论 该优选工艺有效成分提取率高,条件可行,为肺痿颗粒工艺的优化提供科学依据.
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