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Application of drug-loaded nanoparticles in dry powder inhalations
Author(s): 
Pages: 721-724
Year: Issue:  12
Journal: Qilu Pharmaceutical Affairs

Keyword:  载药纳米粒干粉吸入剂喷雾干燥纳米粒-载体复合物纳米粒聚集体;
Abstract: 本文分析了载药纳米粒在干粉吸入剂上缺乏商业吸引力的原因,以及与常规干粉吸入剂相比存在的优势;介绍了纳米粒-载体复合物、大粒径中空纳米粒聚集体两种干粉吸入剂的制备方法及形成机制.由于纳米粒干粉吸入制剂具备优良的分散性能和肺沉积性能,并同时拥有纳米粒作为药物载体的独特性能,使其在干粉吸入剂上具有强大的优势和广阔的发展空间.
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