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Studies on chemical constituents of the flower buds of Tussilago farfara
Pages: 373-375
Year: Issue:  7
Journal: Qilu Pharmaceutical Affairs

Keyword:  Tussilago farfaraAsteraceaeChemical constituen;
Abstract: Objective To study the chemical constituents of the flower buds of Tussilago farfara. Methods The chemical constituents were isolated and purified through silica gel and HPLC chromatography. The structures were elucida-ted on the basis of spectroscopic methods. Results Five compounds were obtained and established as tussilagone(1),14 -acetoxy - 7β -(4 - methylsEnecioyloxyl)- 1α -(2' - methylbutyryloxy)- notonipetranone(2),6 - acetyl - 2,2 - dimeth-ylchroman - 4 - one(3),3,4 - epoxy - 1,8 - diangeloyloxybisabola - 7(14)- 10 - dien - 2 - one(4),and ligucyperonol (5). Conclusion Compounds 3 ~ 5 were isolated from the flower buds of Tussilago farfara for the first time.
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