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Study on the mucociliary toxicity of nimesulide in toads
Pages: 9-10
Year: Issue:  1
Journal: Qilu Pharmaceutical Affairs

Keyword:  尼美舒利鼻腔给药纤毛毒性;
Abstract: 目的 考察尼美舒利对蟾蜍上腭粘膜纤毛运动的影响.方法 采用蟾蜍在体上腭法,考察尼美舒利对蟾蜍上腭粘膜纤毛持续运动时间和对粘膜纤毛形态的影响.结果 尼美舒利对蟾离离体上腭粘膜的纤毛具有一定影响作用,纤毛持续运动百分率为23%,与生理盐水组相比,P<0.05,具有显著性差异.结论 尼美舒利鼻腔给药需慎重.
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