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Research on preparation of Paeonol Sustained-release Tablets
Pages: 523-525
Year: Issue:  9
Journal: Qilu Pharmaceutical Affairs

Keyword:  丹皮酚缓释片释放度;
Abstract: 目的 制备丹皮酚缓释片并对影响体外释药的因素进行考察.方法 采用正交设计法筛选处方;以羟丙甲基纤维素为骨架材料,采用湿法制粒工艺,制备丹皮酚缓释片;并对HPMC规格、稀释剂种类等影响释药的因素进行考察.结果 丹皮酚缓释片的体外释药行为符合Higuchi方程,HPMC的规格对药物的释放影响最大.结论 采用 HPMC作为骨架材料,结合适当的辅料,可制备丹皮酚缓释片.
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