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zuo hua he wu dui ren xue lin ba xi bao sce de ying xiang
Author(s): 
Pages: 102-106
Year: Issue:  2
Journal: Radiation Protection

Keyword:  氚化合物人淋巴细胞SCE分裂周期增殖速度;
Abstract: 本文用不同活度的~3H-TdR及~3H-UdR加入人血淋巴细胞连续培养,以了解氚对细胞分裂周期及SCE频度的影响。两种氚化合物均可使SCE频度增加,并可使细胞分裂周期延缓。SCE频度随氚活度的增加而明显增加。在导致分裂周期延缓程度上~3H-TdR<~3H-UdR。~3H-UdR各组的SCE频度均值均高于相同浓度的~3H-TdR组,除3.7×10~3Bq/mL组外,其他各组与~3H-TdR对应组之间的差异非常显著(t检验,p<0.01)。氚化合物对细胞增殖速度有影响,细胞增殖速度指数(PRI)与SCE频度有关,SCE频度越高,PRI值就越低。
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