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zuo shui zhao she dui xiao shu mao nang hei se su xi bao fen hua de ying xiang
Pages: 98-102
Year: Issue:  2
Journal: Radiation Protection

Keyword:  氚水黑色素细胞毛囊分化;
Abstract: 本文介绍用不同浓度的氚水(HTO)一次腹腔注入怀孕12和15 d 的 C57 BL/6J 雌鼠,观察出生后3.5 d 第一代(F1)仔鼠背部皮肤毛囊黑色素细胞异常率。结果表明,当15 d 龄胎鼠接受氚累积吸收剂量为0.11—0.67 Gy 时,毛囊异常率为1.0%—5.1%;12 d 龄胎鼠接受氚累积吸收剂量为0.12—0.46 Gy 时,毛囊异常率为3.4%—6.0%。说明随着氚累积吸收剂量的增加,毛囊异常率也增加;胚胎早期接受氚照射的 F1代仔鼠皮肤毛囊异常率较高,12 d 龄胎鼠接受氚水照射引起的毛囊异常率比15 d 龄胎鼠的明显增高。
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