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Study on the nasal administration toxicity of chitosan
Author(s): 
Pages: 373-374,376
Year: Issue:  7
Journal: Qilu Pharmaceutical Affairs

Keyword:  壳聚糖鼻腔给药纤毛毒性鼻腔粘膜毒性;
Abstract: 目的 考察壳聚糖的鼻腔给药毒性.方法 采用在体蟾蜍上腭法研究壳聚糖对纤毛运动的影响;采用大鼠鼻腔给药法考察壳聚糖对鼻腔粘膜形态学的影响.结果 壳聚糖对蟾蜍上腭纤毛运动时间无影响;对大鼠鼻腔粘膜形态无影响.结论 壳聚糖无鼻腔毒性.
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