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Uncertainty analysis in the determination of erythromycin material by microbiological method
Pages: 337-339
Year: Issue:  6
Journal: Qilu Pharmaceutical Affairs

Keyword:  微生物检定法红霉素原料效价不确定度分析;
Abstract: 目的 评定以微生物检定法测定红霉素原料含量的不确定度.方法 根据<测量不确定度评定与表示>(JJFI059-1999)中有关规定,对红霉素原料的含量测定进行不确定度来源及大小进行分析和评定.结果 扩展不确定度为24.34 U·mg-1,效价测定结果可表示为(988.6±24.34)U·mg-1.不确定度主要来源为方法设计,其次为溶液稀释.结论 选择适宜的方法设计,尽可能减少稀释次数,可有效减小试验...
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