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Determination of related substances in Isosorbide Dinitrate Sustained Release Tablets by HPLC
Author(s): 
Pages: 277-279
Year: Issue:  5
Journal: Qilu Pharmaceutical Affairs

Abstract: 目的 对硝酸异山梨酯缓释片有关物质进行测定.方法 采用高效液相色谱,用Agilent eclipse XDB-C18柱(4.6×250mm,5μm),流动相为水-甲醇(70:30);流速为1mL·min-1;检测波长为210 nm;柱温为30 ℃.结果 2-单硝酸异山梨酯线性范围为0.4~20μg·mL-1(r=1.0000),平均回收率为100.3% ,RSD为2.2%;单硝酸异山梨酯线性范围为...
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