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Determination of dissolution of Azithromycin for suspension by HPLC
Pages: 280-282
Year: Issue:  5
Journal: Qilu Pharmaceutical Affairs

Abstract: 目的 建立阿奇霉素干混悬剂的溶出度测定方法.方法 采用桨法,以磷酸盐缓冲液(pH6.0)(0.1mol·L-1磷酸二氢钠溶液3000mL,加盐酸约20mL,调节pH值至6.0±0.05)500mL为溶出介质,转速为50r·min-1,溶出时间为30min,用HPLC法进行测定.结果 本方法线性关系良好,平均回收率为100.5%,RSD=1.4%(n=9).结论 本方法简便、准确,可为阿奇霉素干混悬...
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