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Determination related substances of Estazolam by HPLC
Author(s): 
Pages: 660-662
Year: Issue:  11
Journal: QILU PHARMACEUTICAL AFFAIRS

Keyword:  艾司唑仑有关物质高效液相色谱法;
Abstract: 目的 建立HPLC法测定艾司唑仑的有关物质.方法 采用十八烷基键合硅胶为填充剂,甲醇-水(65:35)为流动相,检测波长223nm.结果 艾司唑仑在1.2~2.8μg·ml-1浓度范围内呈良好的线性关系(r=0.9998),RSD为0.56%.检测限为0.02ng.结论 本方法结果准确,可用于艾司唑仑有关物质的控制.
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